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Inhibition of the Keap1/Nrf2 Signaling Pathway Significantly Promotes the Progression of Type 1 Diabetes Mellitus

Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by insulin deficiency due to pancreatic β-cell damage and leads to hyperglycemia. The precise molecular mechanisms of the etiology of T1DM are not completely understood. Oxidative stress and the antioxidant status of pancreatic β...

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Опубликовано в: :Oxid Med Cell Longev
Главные авторы: Lou, Yanmei, Kong, Muyan, Li, Leyan, Hu, Yu, Zhai, Wenjun, Qi, Xiaoxiao, Liu, Zhongqiu, Wu, Jinjun
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884168/
https://ncbi.nlm.nih.gov/pubmed/33628382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/7866720
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