Plasma Cathelicidin is Independently Associated with Reduced Lung Function in COPD: Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort

Rationale: The antimicrobial peptide cathelicidin, also known in humans as LL-37, is a defensin secreted by immune and airway epithelial cells. Deficiencies in this peptide may contribute to adverse pulmonary outcomes in chronic obstructive pulmonary disease (COPD). Objectives: Using clinical and bi...

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Detalhes bibliográficos
Publicado no:Chronic Obstr Pulm Dis
Main Authors: Burkes, Robert M., Ceppe, Agathe S., Couper, David J., Comellas, Alejandro P., Wells, J. Michael, Peters, Stephen P., Criner, Gerard J., Kanner, Richard E., Paine III, Robert, Christenson, Stephanie A., Cooper, Christopher B., Barjaktarevic, Igor Z., Krishnan, Jerry A., Labaki, Wassim W., Han, MeiLan K., Curtis, Jeffrey L., Hansel, Nadia N., Wise, Robert A., Drummond, M. Bradley
Formato: Artigo
Idioma:Inglês
Publicado em: COPD Foundation Inc 2020
Assuntos:
Origianl Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883905/
https://ncbi.nlm.nih.gov/pubmed/33108110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15326/jcopdf.7.4.2020.0142
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