Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins

Nuclear lamin isoforms form fibrous meshworks associated with nuclear pore complexes (NPCs). Using datasets prepared from subpixel and segmentation analyses of 3D–structured illumination microscopy images of WT and lamin isoform knockout mouse embryo fibroblasts, we determined with high precision th...

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Vydáno v:J Cell Biol
Hlavní autoři: Kittisopikul, Mark, Shimi, Takeshi, Tatli, Meltem, Tran, Joseph Riley, Zheng, Yixian, Medalia, Ohad, Jaqaman, Khuloud, Adam, Stephen A., Goldman, Robert D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883741/
https://ncbi.nlm.nih.gov/pubmed/33570570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202007082
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