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Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins

Nuclear lamin isoforms form fibrous meshworks associated with nuclear pore complexes (NPCs). Using datasets prepared from subpixel and segmentation analyses of 3D–structured illumination microscopy images of WT and lamin isoform knockout mouse embryo fibroblasts, we determined with high precision th...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Kittisopikul, Mark, Shimi, Takeshi, Tatli, Meltem, Tran, Joseph Riley, Zheng, Yixian, Medalia, Ohad, Jaqaman, Khuloud, Adam, Stephen A., Goldman, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883741/
https://ncbi.nlm.nih.gov/pubmed/33570570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202007082
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