A novel dual Ca(2+) sensor system regulates Ca(2+)-dependent neurotransmitter release

Ca(2+)-dependent neurotransmitter release requires synaptotagmins as Ca(2+) sensors to trigger synaptic vesicle (SV) exocytosis via binding of their tandem C2 domains—C2A and C2B—to Ca(2+). We have previously demonstrated that SNT-1, a mouse synaptotagmin-1 (Syt1) homologue, functions as the fast Ca...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Li, Lei, Liu, Haowen, Krout, Mia, Richmond, Janet E., Wang, Yu, Bai, Jihong, Weeratunga, Saroja, Collins, Brett M., Ventimiglia, Donovan, Yu, Yi, Xia, Jingyao, Tang, Jing, Liu, Jie, Hu, Zhitao
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883739/
https://ncbi.nlm.nih.gov/pubmed/33570571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202008121
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