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Analgesic and Anti-Inflammatory Effects of Perampanel in Acute and Chronic Pain Models in Mice: Interaction With the Cannabinergic System

Pain conditions, such as neuropathic pain (NP) and persistent inflammatory pain are therapeutically difficult to manage. Previous studies have shown the involvement of glutamate receptor in pain modulation and in particular same of these showed the key role of the AMPA ionotropic glutamate receptor...

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Vydáno v:Front Pharmacol
Hlavní autoři: De Caro, Carmen, Cristiano, Claudia, Avagliano, Carmen, Cuozzo, Mariarosaria, La Rana, Giovanna, Aviello, Gabriella, De Sarro, Giovambattista, Calignano, Antonio, Russo, Emilio, Russo, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883473/
https://ncbi.nlm.nih.gov/pubmed/33597883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.620221
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