Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors

[Image: see text] Novel therapies are required to treat chronic bacterial infections in cystic fibrosis (CF) sufferers. The most common pathogen responsible for these infections is Pseudomonas aeruginosa, which persists within the lungs of CF sufferers despite intensive antibiotic treatment. P. aeru...

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Publicado no:ACS Med Chem Lett
Main Authors: Leiris, Simon, Davies, David T., Sprynski, Nicolas, Castandet, Jérôme, Beyria, Lilha, Bodnarchuk, Michael S., Sutton, Jonathan M., Mullins, Toby M. G., Jones, Mark W., Forrest, Andrew K., Pallin, T. David, Karunakar, Paduri, Martha, Sathish Kumar, Parusharamulu, Battu, Ramula, Ramesh, Kotha, Venkatesh, Pottabathini, Narender, Pothukanuri, Srinivasu, Lemonnier, Marc, Everett, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883467/
https://ncbi.nlm.nih.gov/pubmed/33603968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00554
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