Pseudomonas aeruginosa Elastase Contributes to the Establishment of Chronic Lung Colonization and Modulates the Immune Response in a Murine Model

Chronic infection by Pseudomonas aeruginosa in cystic fibrosis (CF) patients is a major contributor to progressive lung damage and is poorly treated by available antibiotic therapy. An alternative approach to the development of additional antibiotic treatments is to identify complementary therapies...

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Veröffentlicht in:Front Microbiol
Hauptverfasser: Cigana, Cristina, Castandet, Jérôme, Sprynski, Nicolas, Melessike, Medede, Beyria, Lilha, Ranucci, Serena, Alcalá-Franco, Beatriz, Rossi, Alice, Bragonzi, Alessandra, Zalacain, Magdalena, Everett, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836092/
https://ncbi.nlm.nih.gov/pubmed/33510733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.620819
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