hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf

The regulatory circuitry underlying embryonic stem (ES) cell self‐renewal is well defined, but how this circuitry is disintegrated to enable lineage specification is unclear. RNA‐binding proteins (RBPs) have essential roles in RNA‐mediated gene regulation, and preliminary data suggest that they migh...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Wang, Xue, Ping, Changyun, Tan, Puwen, Sun, Chenguang, Liu, Guang, Liu, Tao, Yang, Shuchun, Si, Yanmin, Zhao, Lijun, Hu, Yongfei, Jia, Yuyan, Wang, Xiaoshuang, Zhang, Meili, Wang, Fang, Wang, Dong, Yu, Jia, Ma, Yanni, Huang, Yue
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883296/
https://ncbi.nlm.nih.gov/pubmed/33349972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104729
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