The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA

BACKGROUND: Retention of a subset of introns in spliced polyadenylated mRNA is emerging as a frequent, unexplained finding from RNA deep sequencing in mammalian cells. RESULTS: Here we analyze intron retention in T lymphocytes by deep sequencing polyadenylated RNA. We show a developmentally regulate...

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Detalhes bibliográficos
Main Authors: Cho, Vicky, Mei, Yan, Sanny, Arleen, Chan, Stephanie, Enders, Anselm, Bertram, Edward M, Tan, Andy, Goodnow, Christopher C, Andrews, T Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053824/
https://ncbi.nlm.nih.gov/pubmed/24476532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-1-r26
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