Simultaneous blocking of the pan‐RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma

Melanoma is a very aggressive form of skin cancer. Although BRAF inhibitors have been utilized for melanoma therapy, advanced melanoma patients still face a low five‐year survival rate. Recent studies have shown that CRAF can compensate for BRAF depletion via regulating DNA synthesis to remain melan...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Wu, Ke‐Jia, Ho, Shih‐Hsin, Wu, Chun, Wang, Hui‐Min D., Ma, Dik‐Lung, Leung, Chung‐Hang
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882986/
https://ncbi.nlm.nih.gov/pubmed/33377602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15994
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