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The CB1R rs2023239 receptor gene variant significantly affects the reinforcing effects of nicotine, but not cue reactivity, in human smokers

INTRODUCTION: The cannabinoid CB1 receptor (CB1R) has been shown in preclinical studies to be involved in nicotine reinforcement and relapse‐like behavior. The common single nucleotide polymorphism (SNP) rs2023239 may code for an alternative CB1R protein, alter CB1R expression, and be involved in ni...

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Dades bibliogràfiques
Publicat a:Brain Behav
Autors principals: Chukwueke, Chidera C., Kowalczyk, William J., Gendy, Marie, Taylor, Richard, Tyndale, Rachel F., Le Foll, Bernard, Heishman, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882168/
https://ncbi.nlm.nih.gov/pubmed/33369277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1982
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