Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer

BACKGROUND: Family history of prostate cancer (PCa) is a well-known risk factor, and both common and rare genetic variants are associated with the disease. OBJECTIVE: To detect new genetic variants associated with PCa, capitalizing on the role of family history and more aggressive PCa. DESIGN, SETTI...

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Veröffentlicht in:Eur Urol
Hauptverfasser: Schaid, Daniel J., McDonnell, Shannon K., FitzGerald, Liesel M., DeRycke, Lissa, Fogarty, Zachary, Giles, Graham G., MacInnis, Robert J., Southey, Melissa C., Nguyen-Dumont, Tu, Cancel-Tassin, Geraldine, Cussenot, Oliver, Whittemore, Alice S., Sieh, Weiva, Ioannidis, Nilah Monnier, Hsieh, Chih-Lin, Stanford, Janet L., Schleutker, Johanna, Cropp, Cheryl D., Carpten, John, Hoegel, Josef, Eeles, Rosalind, Kote-Jarai, Zsofia, Ackerman, Michael J., Klein, Christopher J., Mandal, Diptasri, Cooney, Kathleen A., Bailey-Wilson, Joan E., Helfand, Brian, Catalona, William J., Wiklund, Fredrick, Riska, Shaun, Bahetti, Saurabh, Larson, Melissa C., Albright, Lisa Cannon, Teerlink, Craig, Xu, Jianfeng, Isaacs, William, Ostrander, Elaine A., Thibodeau, Stephen N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881048/
https://ncbi.nlm.nih.gov/pubmed/32800727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2020.07.038
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