Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer

BACKGROUND: Family history of prostate cancer (PCa) is a well-known risk factor, and both common and rare genetic variants are associated with the disease. OBJECTIVE: To detect new genetic variants associated with PCa, capitalizing on the role of family history and more aggressive PCa. DESIGN, SETTI...

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Gepubliceerd in:Eur Urol
Hoofdauteurs: Schaid, Daniel J., McDonnell, Shannon K., FitzGerald, Liesel M., DeRycke, Lissa, Fogarty, Zachary, Giles, Graham G., MacInnis, Robert J., Southey, Melissa C., Nguyen-Dumont, Tu, Cancel-Tassin, Geraldine, Cussenot, Oliver, Whittemore, Alice S., Sieh, Weiva, Ioannidis, Nilah Monnier, Hsieh, Chih-Lin, Stanford, Janet L., Schleutker, Johanna, Cropp, Cheryl D., Carpten, John, Hoegel, Josef, Eeles, Rosalind, Kote-Jarai, Zsofia, Ackerman, Michael J., Klein, Christopher J., Mandal, Diptasri, Cooney, Kathleen A., Bailey-Wilson, Joan E., Helfand, Brian, Catalona, William J., Wiklund, Fredrick, Riska, Shaun, Bahetti, Saurabh, Larson, Melissa C., Albright, Lisa Cannon, Teerlink, Craig, Xu, Jianfeng, Isaacs, William, Ostrander, Elaine A., Thibodeau, Stephen N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881048/
https://ncbi.nlm.nih.gov/pubmed/32800727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2020.07.038
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