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HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG)

Prostate cancer has a strong familial component but uncovering the molecular basis for inherited susceptibility for this disease has been challenging. Recently, a rare, recurrent mutation (G84E) in HOXB13 was reported to be associated with prostate cancer risk. Confirmation and characterization of t...

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Auteurs principaux: Xu, Jianfeng, Lange, Ethan M., Lu, Lingyi, Zheng, Siqun L., Wang, Zhong, Thibodeau, Stephen N., Cannon-Albright, Lisa A., Teerlink, Craig C., Camp, Nicola J., Johnson, Anna M., Zuhlke, Kimberly A., Stanford, Janet L., Ostrander, Elaine A., Wiley, Kathleen E., Isaacs, Sarah D., Walsh, Patrick C., Maier, Christiane, Luedeke, Manuel, Vogel, Walther, Schleutker, Johanna, Wahlfors, Tiina, Tammela, Teuvo, Schaid, Daniel, McDonnell, Shannon K., DeRycke, Melissa S., Cancel-Tassin, Geraldine, Cussenot, Olivier, Wiklund, Fredrik, Grönberg, Henrik, Eeles, Ros, Easton, Doug, Kote-Jarai, Zsofia, Whittemore, Alice S., Hsieh, Chih-Lin, Giles, Graham G., Hopper, John L., Severi, Gianluca, Catalona, William J., Mandal, Diptasri, Ledet, Elisa, Foulkes, William D., Hamel, Nancy, Mahle, Lovise, Moller, Pal, Powell, Isaac, Bailey-Wilson, Joan E., Carpten, John D., Seminara, Daniela, Cooney, Kathleen A., Isaacs, William B.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535370/
https://ncbi.nlm.nih.gov/pubmed/23064873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-012-1229-4
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