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Inhibition of Colony-Stimulating Factor-1 Receptor Enhances the Efficacy of Radiotherapy and Reduces Immune Suppression in Glioblastoma

Aim: To use inhibition of colony-stimulating factor-1 receptor (CSF-1R) to target tumor-associated macrophages (TAMs) and improve the efficacy of radiotherapy in glioblastoma (GBM). Materials and Methods: The CSF-1R inhibitor BLZ-945 was used to examine the impact of CSF-1R inhibition on M2 polariza...

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Detalhes bibliográficos
Publicado no:In Vivo
Main Authors: ALMAHARIQ, F. MUAYAD, QUINN, J. THOMAS, KESARWANI, PRAVIN, KANT, SHIVA, MILLER, C. RYAN, CHINNAIYAN, PRAKASH
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880776/
https://ncbi.nlm.nih.gov/pubmed/33402457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.12239
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