Cerebral blood flow and cerebrovascular reactivity are preserved in a mouse model of cerebral microvascular amyloidosis

Impaired cerebrovascular function is an early biomarker for cerebral amyloid angiopathy (CAA), a neurovascular disease characterized by amyloid-β accumulation in the cerebral vasculature, leading to stroke and dementia. The transgenic Swedish Dutch Iowa (Tg-SwDI) mouse model develops cerebral microv...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Munting, Leon P, Derieppe, Marc, Suidgeest, Ernst, Hirschler, Lydiane, van Osch, Matthias JP, Denis de Senneville, Baudouin, van der Weerd, Louise
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2021
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880694/
https://ncbi.nlm.nih.gov/pubmed/33577447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61279
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