TGFβ pathway deregulation and abnormal phospho‐SMAD2/3 staining in hereditary cerebral hemorrhage with amyloidosis‐Dutch type

Hereditary cerebral hemorrhage with amyloidosis‐Dutch type (HCHWA‐D) is an early onset hereditary form of cerebral amyloid angiopathy (CAA) pathology, caused by the E22Q mutation in the amyloid β (Aβ) peptide. Transforming growth factor β1 (TGFβ1) is a key player in vascular fibrosis and in the form...

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Sparad:
Bibliografiska uppgifter
I publikationen:Brain Pathol
Huvudupphovsmän: Grand Moursel, Laure, Munting, Leon P., van der Graaf, Linda M., van Duinen, Sjoerd G., Goumans, Marie‐Jose T. H., Ueberham, Uwe, Natté, Remco, van Buchem, Mark A., van Roon‐Mom, Willeke M. C., van der Weerd, Louise
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028662/
https://ncbi.nlm.nih.gov/pubmed/28557134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12533
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