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Microbial RNAs Pressure Piezo1 to Respond
Serotonin production by enterochromaffin cells (ECs) is microbiota-dependent, but the mechanism of this is unknown. In this issue of Cell, Sugisawa et al. demonstrate that Piezo1 in ECs senses single-strand RNA (ssRNA) from intestinal microbiota to promote serotonin production. Deletion of Piezo1 in...
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| Veröffentlicht in: | Cell |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7880614/ https://ncbi.nlm.nih.gov/pubmed/32763186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.07.015 |
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