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Profiling Esterases in Mycobacterium tuberculosis Using Far-Red Fluorogenic Substrates

Enzyme-activated, fluorogenic probes are powerful tools for studying bacterial pathogens, including Mycobacterium tuberculosis (Mtb). In prior work, we reported two 7-hydroxy-9H- (1,3-dichloro-9,9-dimethylacridin-2-one) (DDAO)-derived acetoxymethyl ether probes for esterase and lipase detection. Her...

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Détails bibliographiques
Publié dans:ACS Chem Biol
Auteurs principaux: Tallman, Katie R., Levine, Samantha R., Beatty, Kimberly E.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880554/
https://ncbi.nlm.nih.gov/pubmed/27177211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00233
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