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Small-Molecule Probes Reveal Esterases with Persistent Activity in Dormant and Reactivating Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is the deadliest bacterial pathogen in the world. An estimated one-third of humans harbor Mtb in a dormant state. These asymptomatic, latent infections impede tuberculosis eradication due to the long-term potential for reactivation. Dormant Mtb has reduced enzymatic...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Tallman, Katie R., Levine, Samantha R., Beatty, Kimberly E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880555/
https://ncbi.nlm.nih.gov/pubmed/27690385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00135
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