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The effects of early-life growth hormone intervention on tissue specific histone H3 modifications in long-lived Ames dwarf mice

Histone modifications, specifically in the lysine residues of histone H3, have been implicated in lifespan regulation in several model organisms. Our previous studies showed that growth hormone (GH) treatment during early life can dramatically influence lifespan in long-lived Ames dwarf mice. Howeve...

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Pubblicato in:Aging (Albany NY)
Autori principali: Zhang, Fang, Icyuz, Mert, Bartke, Andrzej, Sun, Liou Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880366/
https://ncbi.nlm.nih.gov/pubmed/33378746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202451
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