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MiR-16-5p suppresses myofibroblast activation in systemic sclerosis by inhibiting NOTCH signaling

Systemic sclerosis (SSc) is a prototypic fibrotic disease characterized by localized or diffuse skin thickening and fibrosis. Tissue fibrosis is driven by myofibroblasts, and factors affecting myofibroblast activation may also be involved in the development of SSc. In this study, we examined molecul...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Yao, Qicen, Xing, Yixi, Wang, Zaiyan, Liang, Jin, Lin, Qianqi, Huang, Meiqiong, Chen, Yiling, Lin, Bo, Xu, Xiayu, Chen, Weifei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880343/
https://ncbi.nlm.nih.gov/pubmed/33411678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202308
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