p16(INK4a) Translation Suppressed by miR-24

BACKGROUND: Expression of the tumor suppressor p16(INK4a) increases during aging and replicative senescence. METHODOLOGY/PRINCIPAL FINDINGS: Here, we report that the microRNA miR-24 suppresses p16 expression in human diploid fibroblasts and cervical carcinoma cells. Increased p16 expression with rep...

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Autors principals: Lal, Ashish, Kim, Hyeon Ho, Abdelmohsen, Kotb, Kuwano, Yuki, Pullmann, Rudolf, Srikantan, Subramanya, Subrahmanyam, Ramesh, Martindale, Jennifer L., Yang, Xiaoling, Ahmed, Fariyal, Navarro, Francisco, Dykxhoorn, Derek, Lieberman, Judy, Gorospe, Myriam
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2274865/
https://ncbi.nlm.nih.gov/pubmed/18365017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001864
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