Chondroitinase and Antidepressants Promote Plasticity by Releasing TRKB from Dephosphorylating Control of PTPσ in Parvalbumin Neurons

Perineuronal nets (PNNs) are an extracellular matrix structure rich in chondroitin sulfate proteoglycans (CSPGs), which preferentially encase parvalbumin-containing (PV(+)) interneurons. PNNs restrict cortical network plasticity but the molecular mechanisms involved are unclear. We found that reacti...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Lesnikova, Angelina, Casarotto, Plinio Cabrera, Fred, Senem Merve, Voipio, Mikko, Winkel, Frederike, Steinzeig, Anna, Antila, Hanna, Umemori, Juzoh, Biojone, Caroline, Castrén, Eero
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2021
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880295/
https://ncbi.nlm.nih.gov/pubmed/33293360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2228-20.2020
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