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Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors
BACKGROUND: Administration of anandamide (AEA) or 2-arachidonoylglycerol (2AG) induces CB1 coupling and activation of TRKB receptors, regulating the neuronal migration and maturation in the developing cortex. However, at higher concentrations AEA also engages vanilloid receptor TRPV1, usually with o...
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| Publicado no: | PeerJ |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
PeerJ Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6387754/ https://ncbi.nlm.nih.gov/pubmed/30809460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.6493 |
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