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Neuropathological Characterization of a Dravet Syndrome Knock-In Mouse Model Useful for Investigating Cannabinoid Treatments

Dravet syndrome (DS) is an epileptic syndrome caused by mutations in the Scn1a gene encoding the α1 subunit of the sodium channel Nav1.1, which is associated with febrile seizures that progress to severe tonic-clonic seizures and associated comorbidities. Treatment with cannabidiol has been approved...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Satta, Valentina, Alonso, Cristina, Díez, Paula, Martín-Suárez, Soraya, Rubio, Marta, Encinas, Juan M., Fernández-Ruiz, Javier, Sagredo, Onintza
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879984/
https://ncbi.nlm.nih.gov/pubmed/33584198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.602801
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