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Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington’s Disease: Role of CB(1) and CB(2) Receptors

[Image: see text] We have investigated whether a 1:1 combination of botanical extracts enriched in either Δ(9)-tetrahydrocannabinol (Δ(9)-THC) or cannabidiol (CBD), which are the main constituents of the cannabis-based medicine Sativex, is neuroprotective in Huntington’s disease (HD), using an exper...

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Detalhes bibliográficos
Main Authors: Valdeolivas, Sara, Satta, Valentina, Pertwee, Roger G., Fernández-Ruiz, Javier, Sagredo, Onintza
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382456/
https://ncbi.nlm.nih.gov/pubmed/22860209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200114w
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