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Cannabinoid CB(2) receptor agonists protect the striatum against malonate toxicity: relevance for Huntington’s disease
Cannabinoid agonists might serve as neuroprotective agents in neurodegenerative disorders. Here, we examined this hypothesis in a rat model of Huntington’s disease (HD) generated by intrastriatal injection of the mitochondrial complex II inhibitor malonate. Our results showed that only compounds abl...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706932/ https://ncbi.nlm.nih.gov/pubmed/19115380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20838 |
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