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The challenging nature of primary T lymphocytes for transfection: Effect of protamine sulfate on the transfection efficiency of chemical transfection reagents

BACKGROUND AND PURPOSE: The optimization of an effective non-viral gene delivery method for genetic manipulation of primary human T cells has been a major challenge in immunotherapy researches. Due to the poor transfection efficiency of conventional methods in T cells, there has been an effort to in...

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Pubblicato in:Res Pharm Sci
Autori principali: Rahimmanesh, Ilnaz, Totonchi, Mehdi, Khanahmad, Hossein
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer - Medknow 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879792/
https://ncbi.nlm.nih.gov/pubmed/33628285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.297846
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