Umbilical mesenchymal stem cell-derived exosomes facilitate spinal cord functional recovery through the miR-199a-3p/145-5p-mediated NGF/TrkA signaling pathway in rats

BACKGROUND: Although exosomes, as byproducts of human umbilical cord mesenchymal stem cells (hUC-MSCs), have been demonstrated to be an effective therapy for traumatic spinal cord injury (SCI), their mechanism of action remains unclear. METHODS: We designed and performed this study to determine whet...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Wang, Yang, Lai, Xunwei, Wu, Depeng, Liu, Bin, Wang, Nanxiang, Rong, Limin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879635/
https://ncbi.nlm.nih.gov/pubmed/33579361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02148-5
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi