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Mucopolysaccharidosis Type VI in a Great Dane Dog Caused by a Nonsense Mutation in the ARSB Gene

Mucopolysaccharidoses (MPS) are inherited metabolic disorders that result from a deficiency of lysosomal enzymes required for the catabolism of glycosaminoglycans (GAG). Lysosomal GAG accumulation results in cell and organ dysfunction. This study characterizes the phenotype and genotype of MPS VI in...

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Detalhes bibliográficos
Publicado no:Vet Pathol
Main Authors: Wang, P., Margolis, C., Lin, G., Buza, E. L., Quick, S., Raj, K. R., Han, R., Giger, U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879606/
https://ncbi.nlm.nih.gov/pubmed/29157190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300985817732115
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