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cMyBP-C phosphorylation modulates the time-dependent slowing of unloaded shortening in murine skinned myocardium
In myocardium, phosphorylation of cardiac myosin-binding protein-C (cMyBP-C) is thought to modulate the cooperative activation of the thin filament by binding to myosin and/or actin, thereby regulating the probability of cross-bridge binding to actin. At low levels of Ca(2+) activation, unloaded sho...
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| Udgivet i: | J Gen Physiol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Rockefeller University Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7879488/ https://ncbi.nlm.nih.gov/pubmed/33566084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012782 |
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