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Bioorthogonal mRNA labeling at the poly(A) tail for imaging localization and dynamics in live zebrafish embryos

Live imaging of mRNA in cells and organisms is important for understanding the dynamic aspects underlying its function. Ideally, labeling of mRNA should not alter its structure or function, nor affect the biological system. However, most methods applied in vivo make use of genetically encoded tags a...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Westerich, Kim J., Chandrasekaran, Karthik S., Gross-Thebing, Theresa, Kueck, Nadine, Raz, Erez, Rentmeister, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879197/
https://ncbi.nlm.nih.gov/pubmed/33623655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05981d
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