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Susceptibility of global HIV-1 clinical isolates to fostemsavir using the PhenoSense(®) Entry assay
BACKGROUND: Fostemsavir is a prodrug of a first-in-class HIV-1 attachment inhibitor, temsavir, that binds to gp120 and blocks attachment to the host-cell CD4 receptor, preventing entry and infection of the target cell. Previous studies using a limited number of clinical isolates showed that there wa...
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| Опубликовано в: : | J Antimicrob Chemother |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7879148/ https://ncbi.nlm.nih.gov/pubmed/33241285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa474 |
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