Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection

SARS-CoV-2 has caused the global COVID-19 pandemic. Although passively delivered neutralizing antibodies against SARS-CoV-2 show promise in clinical trials, their mechanism of action in vivo is incompletely understood. Here, we define correlates of protection of neutralizing human monoclonal antibod...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Winkler, Emma S., Gilchuk, Pavlo, Yu, Jinsheng, Bailey, Adam L., Chen, Rita E., Chong, Zhenlu, Zost, Seth J., Jang, Hyesun, Huang, Ying, Allen, James D., Case, James Brett, Sutton, Rachel E., Carnahan, Robert H., Darling, Tamarand L., Boon, Adrianus C.M., Mack, Matthias, Head, Richard D., Ross, Ted M., Crowe, James E., Diamond, Michael S.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Inc. 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879018/
https://ncbi.nlm.nih.gov/pubmed/33691139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.02.026
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