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Eliminating mesothelioma by AAV-vectored, PD1-based vaccination in the tumor microenvironment
The potency of cancer vaccines is often compromised by a variety of immunoinhibitory mechanisms, including stimulation of the programmed cell death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) immune checkpoint pathway. Here, to overcome inhibition, we determined the potential of recombinant a...
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| Publicat a: | Mol Ther Oncolytics |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Gene & Cell Therapy
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7878991/ https://ncbi.nlm.nih.gov/pubmed/33614918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2021.01.010 |
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