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NASH-related increases in plasma bile acid levels depend on insulin resistance

BACKGROUND & AIMS: Plasma bile acids (BAs) have been extensively studied as pathophysiological actors in non-alcoholic steatohepatitis (NASH). However, results from clinical studies are often complicated by the association of NASH with type 2 diabetes (T2D), obesity, and insulin resistance (IR)....

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Veröffentlicht in:JHEP Rep
Hauptverfasser: Grzych, Guillaume, Chávez-Talavera, Oscar, Descat, Amandine, Thuillier, Dorothée, Verrijken, An, Kouach, Mostafa, Legry, Vanessa, Verkindt, Hélène, Raverdy, Violeta, Legendre, Benjamin, Caiazzo, Robert, Van Gaal, Luc, Goossens, Jean-Francois, Paumelle, Réjane, Francque, Sven, Pattou, François, Haas, Joel T., Tailleux, Anne, Staels, Bart
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878982/
https://ncbi.nlm.nih.gov/pubmed/33615207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100222
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