Designed folding pathway of modular coiled-coil-based proteins

Natural proteins are characterised by a complex folding pathway defined uniquely for each fold. Designed coiled-coil protein origami (CCPO) cages are distinct from natural compact proteins, since their fold is prescribed by discrete long-range interactions between orthogonal pairwise-interacting coi...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Aupič, Jana, Strmšek, Žiga, Lapenta, Fabio, Pahovnik, David, Pisanski, Tomaž, Drobnak, Igor, Ljubetič, Ajasja, Jerala, Roman
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878764/
https://ncbi.nlm.nih.gov/pubmed/33574262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21185-5
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