A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures

Coiled-coil (CC) dimers are widely used in protein design because of their modularity and well-understood sequence–structure relationship. In CC protein origami design, a polypeptide chain is assembled from a defined sequence of CC building segments that determine the self-assembly of protein cages...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Majerle, Andreja, Hadži, San, Aupič, Jana, Satler, Tadej, Lapenta, Fabio, Strmšek, Žiga, Lah, Jurij, Loris, Remy, Jerala, Roman
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092592/
https://ncbi.nlm.nih.gov/pubmed/33893235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021899118
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