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Stabilization of the Hinge Region of Human E-selectin Enhances Binding Affinity to Ligands Under Force

INTRODUCTION: E-selectin is a member of the selectin family of cell adhesion molecules expressed on the plasma membrane of inflamed endothelium and facilitates initial leukocyte tethering and subsequent cell rolling during the early stages of the inflammatory response via binding to glycoproteins ex...

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Publicat a:Cell Mol Bioeng
Autors principals: Cao, Thong M., King, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878631/
https://ncbi.nlm.nih.gov/pubmed/33633813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-021-00666-z
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