Minimal Residual Disease Detection by Next-Generation Sequencing in Multiple Myeloma: A Comparison With Real-Time Quantitative PCR

Here we compared clonotype identification by allele-specific oligonucleotide real-time quantitative-PCR (ASO RQ-PCR) and next-generation sequencing (NGS) in 80 multiple myeloma patients. ASO RQ-PCR was applicable in 49/55 (89%) and NGS in 62/78 (80%). Clonotypes identified by both methods were ident...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Yao, Qiumei, Bai, Yinlei, Kumar, Shaji, Au, Elaine, Orfao, Alberto, Chim, Chor Sang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878533/
https://ncbi.nlm.nih.gov/pubmed/33585233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.611021
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