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Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone

The Hsp40/Hsp70 chaperone families combine versatile folding capacity with high substrate specificity, which is mainly facilitated by Hsp40s. The structure and function of many Hsp40s remain poorly understood, particularly oligomeric Hsp40s that suppress protein aggregation. Here, we used a combinat...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Ryder, Bryan D., Matlahov, Irina, Bali, Sofia, Vaquer-Alicea, Jaime, van der Wel, Patrick C. A., Joachimiak, Lukasz A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878476/
https://ncbi.nlm.nih.gov/pubmed/33574241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21147-x
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