The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation

Th17 cells are known to exert both pathogenic and non-pathogenic functions. While the cytokine TGF-β1 is instrumental to Th17 cell differentiation, it is dispensible for the generation of pathogenic-Th17 cells. Here, we examined the T cell-intrinsic role of Activin-A, a TGF-β superfamily member clos...

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Detaylı Bibliyografya
Yayımlandı:Immunity
Asıl Yazarlar: Wu, Bing, Zhang, Song, Guo, Zengli, Bi, Yanmin, Zhou, Mingxia, Li, Ping, Seyedsadr, Maryamsadat, Xu, Xiaojiang, Li, Jian-liang, Markovic-Plese, Silva, Wan, Yisong Y
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878438/
https://ncbi.nlm.nih.gov/pubmed/33421362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.12.010
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