The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation

Th17 cells are known to exert both pathogenic and non-pathogenic functions. While the cytokine TGF-β1 is instrumental to Th17 cell differentiation, it is dispensible for the generation of pathogenic-Th17 cells. Here, we examined the T cell-intrinsic role of Activin-A, a TGF-β superfamily member clos...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Wu, Bing, Zhang, Song, Guo, Zengli, Bi, Yanmin, Zhou, Mingxia, Li, Ping, Seyedsadr, Maryamsadat, Xu, Xiaojiang, Li, Jian-liang, Markovic-Plese, Silva, Wan, Yisong Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878438/
https://ncbi.nlm.nih.gov/pubmed/33421362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.12.010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados