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A Class of Viral Inducer of Degradation of the Necroptosis Adaptor RIPK3 Regulates Virus-Induced Inflammation

The vaccine strain against smallpox, vaccinia virus (VACV), is highly immunogenic yet causes relatively benign disease. These attributes are believed to be caused by gene loss in VACV. Using a targeted siRNA screen, we identified a viral inhibitor found in cowpox virus (CPXV) and other orthopoxvirus...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Liu, Zhijun, Nailwal, Himani, Rector, Jonah, Rahman, Masmudur M., Sam, Richard, McFadden, Grant, Chan, Francis Ka-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878414/
https://ncbi.nlm.nih.gov/pubmed/33444549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.11.020
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