C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism

Chronic hepatitis B virus (HBV) infection is strongly associated with the initiation and development of hepatocellular carcinoma (HCC). However, the genetic alterations and pathogenesis mechanisms remain significantly unexplored, especially for HBV-induced metabolic reprogramming. Analysis of integr...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Zhang, Yu, Yan, Qian, Gong, Lanqi, Xu, Hang, Liu, Beilei, Fang, Xiaona, Yu, Dandan, Li, Lei, Wei, Ting, Wang, Ying, Wong, Ching Ngar, Lyu, Zhaojie, Tang, Ying, Sham, Pak Chung, Guan, Xin-Yuan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878188/
https://ncbi.nlm.nih.gov/pubmed/33323975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01593-5
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