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Pharmacokinetics and Pharmacodynamics of Cenerimod, A Selective S1P(1)R Modulator, Are Not Affected by Ethnicity in Healthy Asian and White Subjects

Cenerimod is a sphingosine‐1‐phosphate 1 receptor (S1P(1)R) modulator in phase II development for treatment of systemic lupus erythematosus. Its pharmacokinetics (PKs), pharmacodynamics (PDs), as well as safety and tolerability were investigated in white and Asian subjects to allow for recruitment o...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Juif, Pierre‐Eric, Dingemanse, Jasper, Winkle, Peter, Ufer, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877840/
https://ncbi.nlm.nih.gov/pubmed/32860737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12873
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