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Population Pharmacokinetics of Candesartan in Patients with Chronic Heart Failure

Heart failure (HF) causes pathological changes in multiple organs, thus affecting the pharmacokinetics (PK) of drugs. The aim of this study was to investigate the PK of candesartan in patients with HF while examining significant covariates and their related impact on estimated clearance using a popu...

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Publicat a:Clin Transl Sci
Autors principals: Kassem, Imad, Sanche, Steven, Li, Jun, Bonnefois, Guillaume, Dubé, Marie‐Pierre, Rouleau, Jean‐Lucien, Tardif, Jean‐Claude, White, Michel, Turgeon, Jacques, Nekka, Fahima, de Denus, Simon
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877833/
https://ncbi.nlm.nih.gov/pubmed/32702160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12842
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