ASC-dependent inflammasomes contribute to immunopathology and mortality in herpes simplex encephalitis

Herpes simplex virus encephalitis (HSE) is the most common cause of sporadic viral encephalitis, and despite targeted antiviral therapy, outcomes remain poor. Although the innate immune system is critical for restricting herpes simplex virus type I (HSV-1) in the brain, there is evidence that prolon...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Hayes, Cooper K., Wilcox, Douglas R., Yang, Yuchen, Coleman, Grace K., Brown, Melissa A., Longnecker, Richard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877773/
https://ncbi.nlm.nih.gov/pubmed/33524073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009285
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