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Conserved amino acids in the region connecting membrane spanning domain 1 to nucleotide binding domain 1 are essential for expression of the MRP1 (ABCC1) transporter
Multidrug resistance protein 1 (MRP1) (gene symbol ABCC1) is an ATP-binding cassette (ABC) transporter which effluxes xeno- and endobiotic organic anions including estradiol glucuronide and the pro-inflammatory leukotriene C(4). MRP1 also confers multidrug resistance by reducing intracellular drug a...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7877750/ https://ncbi.nlm.nih.gov/pubmed/33571281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246727 |
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